For many living with major depressive disorder, the journey to find relief can feel like a cycle of trial and error. You try a medication, wait weeks for results, and often find that the “cloud” hasn’t lifted. If you have tried two or more antidepressants without significant improvement, you may be experiencing Treatment-Resistant Depression (TRD).
At Anaheim Community Hospital, we understand that “standard” care isn’t always enough. That is why our Behavioral Health team offers Spravato® (esketamine) nasal spray—a breakthrough, FDA-approved treatment specifically designed for adults who haven’t found relief through traditional oral medications.
What is Treatment-Resistant Depression?
Treatment-Resistant Depression is a term used by mental health professionals when a patient does not respond adequately to at least two different antidepressant cycles of adequate dose and duration. It is more common than many realize, affecting approximately one-third of adults treated for major depression.
How is Spravato Different from Regular Antidepressants?
Most traditional antidepressants (like SSRIs or SNRIs) work by increasing levels of neurotransmitters like serotonin or norepinephrine in the brain. While effective for many, they can take weeks or even months to show results.
Spravato (Esketamine) targets the NMDA receptor and works on glutamate, the most abundant chemical messenger in the brain. This pathway helps create new neural connections, essentially “rewiring” parts of the brain involved in mood and emotional regulation. Many patients report feeling a difference much sooner than with traditional pills.
What to Expect at the Spravato Treatment Clinic in Anaheim
Safety and comfort are our top priorities. Because Spravato is a prescription nasal spray administered under medical supervision, our clinic provides a structured, calming environment for your sessions:
- Medical Supervision: You will self-administer the nasal spray under the guidance of our healthcare providers.
- Observation Period: After administration, you will rest in a comfortable, private setting for about two hours while our staff monitors your vitals and ensures you are reacting well to the treatment.
- Comprehensive Care: Spravato is taken in conjunction with an oral antidepressant, providing a dual-layered approach to your recovery.
Why Choose Anaheim Community Hospital for Behavioral Health?
Choosing a hospital-based clinic for your TRD treatment ensures a higher level of clinical oversight. Our specialized Spravato Treatment Clinic is staffed by board-certified psychiatrists and experienced mental health professionals who are dedicated to the Orange County community. We offer a continuum of care, meaning we can support you through outpatient therapy, intensive treatments, and beyond.
Frequently Asked Questions (FAQ)
Q: Does insurance cover Spravato therapy?
A: Many commercial insurance plans and Medicare provide coverage for Spravato for patients who meet the criteria for Treatment-Resistant Depression. Our intake team can help you navigate the authorization process.
Q: How many sessions of Spravato will I need?
A: Treatment typically begins with two sessions per week for the first month, eventually transitioning to once a week or once every two ages during the maintenance phase, depending on your clinical response.
Q: Can I drive home after my appointment?
A: No. Because Spravato can cause temporary sedation or dissociation, patients must arrange for a ride home after their two-hour observation period. You will be able to drive again the following day after a full night’s sleep.
Take the First Step Toward Relief
You don’t have to settle for “good enough” when it comes to your mental health. If you are struggling with depression that won’t go away, it may be time to explore advanced options.
Contact the Anaheim Community Hospital Behavioral Health Team today to schedule a confidential consultation.